2-Bromo Propionic Acid

AD PHARMACHEM is known for manufacturer of 2-Bromo Propionic Acid intermediates.

 

 

2-Bromo Propionic Acid, also known as α-bromopropionic acid, is an organic compound with the molecular formula C3H5BrO2. It is a derivative of propionic acid, where a bromine atom is substituted at the alpha (2nd) position of the propionic acid molecule. This compound belongs to the class of haloalkanoic acids, which are characterized by the presence of a halogen atom attached to an aliphatic carboxylic acid. 

 

 

This chemical is used in various applications, including organic synthesis and as an intermediate in pharmaceutical manufacturing.

 

 

Synthesis

 

2-Bromo propionic acid can be synthesized through the bromination of propionic acid using bromine (Br2) in the presence of a catalyst. The reaction typically involves:

 

  • Mixing propionic acid with bromine.
  • Adding a catalyst such as red phosphorus or a similar bromine carrier.
  • Heating the mixture to facilitate the substitution reaction.

2-Bromo Propionic Acid Physical & Chemical Properties

1. Molecular Formula: C3H5BrO2

2. Molecular Weight: 152.98 g/mol

 

3. Appearance: Colorless to pale yellow liquid

 

4. Melting Point: 25-30°C

 

5. Boiling Point: 170-172°C at 760 mmHg

 

6. Density: 1.672 g/cm³

 

7. Solubility: Soluble in water, ethanol, and other organic solvents

 

8. Odor: Pungent, characteristic of carboxylic acids

2-Bromo Propionic Acid

Applications of 2-Bromo Propionic Acid

1. Intermediate in Organic Synthesis: 2-Bromo Propionic Acid is extensively used as an intermediate in the synthesis of various organic compounds. It serves as a key building block in the preparation of alpha-substituted propionic acids and other derivatives.

2. Pharmaceuticals: In the pharmaceutical industry, it is used in the synthesis of active pharmaceutical ingredients (APIs) and other drug intermediates. Its ability to undergo substitution reactions makes it valuable in the development of various bioactive molecules.

 

3. Agricultural Chemicals: It is used in the production of agrochemicals, including herbicides and pesticides, where its reactivity is harnessed to create compounds with specific biological activities.

 

4. Polymer Chemistry: 2-Bromo Propionic Acid is employed in polymer chemistry as a monomer or as a functional group modifier in the synthesis of polymers and copolymers. Its incorporation into polymer chains can modify the physical properties of the resulting materials.

 

5. Research and Development: This compound is widely used in chemical research and development, especially in studies involving halogenated carboxylic acids and their derivatives.