4-Bromo Benzaldehyde

AD PHARMACHEM is known for manufacturer of 4-Bromo Benzaldehyde intermediates.


4-Bromo Benzaldehyde, also known as para-bromobenzaldehyde, is an organic compound with the molecular formula C7H5BrO. It belongs to the class of aromatic aldehydes, which are characterized by the presence of an aldehyde group (-CHO) attached to a benzene ring. In 4-Bromo Benzaldehyde, a bromine atom is substituted at the para (4th) position relative to the aldehyde group on the benzene ring.

 We are manufacturer of high-quality API Intermediats, 4-Bromo benzaldehyde is a colorless liquid. It displays reactivity characteristic of benzaldehyde and an aryl bromide. 4-Bromobenzaldehyde – plays an important role in palladium-catalyzed mono-and bis-arylation of 3,4-(ethylenedioxy)thiophenes. It is employed in a cross-coupling study with potassium vinyltrifluoroborate.4-Bromobenzaldehyde, or p-bromobenzaldehyde, is an organobromine compound with the formula BrC 6H 4CHO. It is one of three isomers of bromobenzaldehyde.

4-Bromo Benzaldehyde Physical and Chemical Properties

1. Molecular Formula: C7H5BrO

 

2. Molecular Weight: 185.02 g/mol

 

3. Appearance: White to off-white crystalline powder

 

4. Melting Point: 58-60°C

 

5. Boiling Point: 224-226°C at 760 mmHg

 

6. Density: 1.557 g/cm³

 

7. Solubility: Slightly soluble in water; soluble in organic solvents like ethanol, ether, and chloroform.

 

8. Flash Point: 93°C

 

9. Odor: Aromatic, characteristic of benzaldehyde derivatives

  • Chemical Reactivity: 4-Bromo Benzaldehyde exhibits typical aldehyde reactions, including oxidation to form the corresponding carboxylic acid (4-bromobenzoic acid) and reduction to form the corresponding alcohol (4-bromobenzyl alcohol). The presence of the bromine atom makes the molecule more reactive towards nucleophilic substitution reactions.
  • Stability: Stable under normal conditions, but it should be stored in a cool, dry place, away from strong oxidizing agents.
4-Bromo Benzaldehyde

Applications of 4-Bromo Benzaldehyde

Intermediate in Organic Synthesis: 4-Bromo Benzaldehyde is widely used as an intermediate in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and dyes. It serves as a key building block for the production of other brominated aromatic compounds.

 

1. Pharmaceuticals: In the pharmaceutical industry, 4-Bromo Benzaldehyde is used in the synthesis of active pharmaceutical ingredients (APIs) and other drug intermediates.

 

2. Agrochemicals: It is utilized in the development of pesticides and herbicides due to its ability to undergo further chemical transformations, leading to the formation of bioactive compounds.

 

3. Perfume and Fragrance Industry: Due to its aromatic aldehyde structure, it is sometimes used as a component in the manufacture of fragrances and flavors, contributing to the development of scents with aldehyde notes.

 

4. Research and Development: 4-Bromo Benzaldehyde is often used in chemical research and development as a starting material for the synthesis of more complex molecules.