N-Butyl Bromide (NBB)
AD PHARMACHEM is known for manufacturer of N-Butyl Bromide (NBS) intermediates.
N-Butyl bromide, also known as 1-bromobutane, is an organic compound with the chemical formula C4H9Br.
It belongs to the class of alkyl bromides, which are compounds containing a bromine atom bonded to an alkyl group. Insoluble in water, but soluble in organic solvents, is the colorless liquid known as n-butyl bromide. It is primarily used as an alkylating agent in organic synthesis and as a starting material in the production of pharmaceuticals and other organic compounds.
N-Butyl Bromide Industrial Application
N-Butyl Bromide is a clear, colorless liquid that plays a crucial role in various industrial applications.
1. Solubility:
NBB is known for its solubility characteristics. It is insoluble in water, which limits its use in aqueous solutions. However, it exhibits excellent solubility in alcohol and ether, making it highly versatile for use in organic synthesis and other industrial processes where these solvents are prevalent.
2. Moisture Content:
Maintaining the integrity of NBB is essential for its efficacy. The moisture content of NBB is controlled to be Not More Than (NMT) 0.1%. This stringent specification ensures the chemical’s stability and effectiveness in its applications.
3. Boiling Point:
N-Butyl Bromide has a boiling point of 101 °C.
4. Specific Gravity @ 25 °C:
The specific gravity of N-Butyl Bromide at 25 °C ranges from 1.265 to 1.275 g/ml.
5. Chromatographic Purity by Gas Chromatography (GC) % Area Normalization:
The purity of N-Butyl Bromide is rigorously assessed using gas chromatography (GC), ensuring that it meets the highest standards for industrial and laboratory use. The GC method provides an accurate measure of the chemical’s composition, crucial for quality control and assurance.
6. % Purity:
N-Butyl Bromide boasts a purity level of Not Less Than (NLT) 99.00%. This high purity is essential for its use in sensitive applications, where impurities could significantly affect the outcome.
7. % Total Impurities:
The total impurities in N-Butyl Bromide are controlled to be Not More Than (NMT) 1.0%. Keeping impurities to a minimum ensures the chemical’s reliability and consistency, crucial for its role in various industrial processes.
Application of of N-Butyl Bromide
N-Butyl Bromide is used in laboratory applications:
1. Alkylating Agent: In organic synthesis, NBB is used to introduce a butyl group into organic molecules, a process known as alkylation. It reacts with nucleophiles such as alcohols, amines, or thiols to form ethers, amines, and thioethers, respectively.
