Tetra Ethyl Ammonium Bromide

Tetra ethyl ammonium bromide is a quaternary ammonium compound that consists of a bromide ion and a nitrogen atom bound to four ethyl groups. This compound is widely used in research, particularly in the study of ion channels, and has applications in organic synthesis and as a phase transfer catalyst.

 

Chemical Formula: C8H20BrN

Molecular Weight: 210.16 g/mol

 

CAS Number: 71-91-0

Physical and Chemical Properties Tetra ethyl ammonium bromide

1. Appearance: White crystalline solid or powder

 

2. Solubility: Highly soluble in water

Soluble in alcohols like methanol and ethanol

 

3. Melting Point: 285-290°C (545-554°F)

 

4. Boiling Point: Decomposes before boiling

 

5. Density: Approximately 1.2 g/cm³

 

6. Odor: Odorless

Tetra Ethyl Ammonium Bromide

Chemical Properties:

  • Quaternary Ammonium Compound: Contains a nitrogen atom bonded to four ethyl groups, resulting in a positively charged ion paired with a bromide ion.
  • Stability: Stable under normal conditions, but may decompose when exposed to strong oxidizing agents or high temperatures.
  • Reactivity:

1. Acts as a mild base.

2. Can participate in phase transfer catalysis.

3. Incompatible with strong acids and oxidizing agents.

Application of Tetra ethyl ammonium bromide

1. Ion Channel Research:

 

Tetraethylammonium bromide is widely used in neuroscience and pharmacology research to block potassium channels in neurons and other cells. This allows scientists to study the function of ion channels and their role in cellular processes.

 

2. Phase Transfer Catalyst:

 

The compound is used as a phase transfer catalyst in organic synthesis, where it facilitates the transfer of reactants between immiscible phases, such as aqueous and organic layers, thereby enhancing reaction rates and yields.

 

3. Organic Synthesis:

 

Tetraethylammonium bromide serves as a reagent in various organic reactions, including alkylation processes, where it helps introduce quaternary ammonium groups into molecules.

 

4. Electrochemistry:

 

It is also utilized in electrochemical applications, particularly in the preparation of electrolytes for electroplating and other processes that require enhanced conductivity.

 

5. Chemical Industry:

 

The compound is employed in the production of specialty chemicals and as a precursor in the synthesis of other quaternary ammonium salts.